Hysbysiad contract
Adran I:
Endid
contractio
I.1) Enw a chyfeiriad
University of Dundee
Procurement, 3rd Floor, Tower Building, Nethergate
Dundee
DD1 4HN
UK
Person cyswllt: Mary Kirkpatrick
Ffôn: +44 1382386604
E-bost: m.y.kirkpatrick@dundee.ac.uk
NUTS: UKM71
Cyfeiriad(au) rhyngrwyd
Prif gyfeiriad: http://www.dundee.ac.uk
Cyfeiriad proffil y prynwr: https://www.publiccontractsscotland.gov.uk/search/Search_AuthProfile.aspx?ID=AA00105
I.2) Caffael ar y cyd
Caiff y contract ei ddyfarnu gan gorff prynu canolog
I.3) Cyfathrebu
Mae'r dogfennau caffael ar gael ar gyfer mynediad uniongyrchol anghyfyngedig a llawn, yn rhad ac am ddim ar:
www.publiccontractsscotland.gov.uk
Gellir cael gwybodaeth ychwanegol o'r cyfeiriad uchod
Rhaid anfon tendrau neu geisiadau i gymryd rhan yn electronig at:
www.publicontractsscotland.gov.uk
Mae cyfathrebu electronig yn gofyn am ddefnyddio offer a dyfeisiau nad ydynt ar gael yn gyffredinol. Mae mynediad uniongyrchol anghyfgyfyngiedig a llawn i'r offer a dyfeisiau hyn yn bosibl, yn rhad ac am ddim, yn:
www.publicontractsscotland.gov.uk
I.4) Y math o awdurdod contractio
Corff a lywodraethir gan gyfraith gyhoeddus
I.5) Prif weithgaredd
Addysg
Adran II: Gwrthrych
II.1) Cwmpas y caffaeliad
II.1.1) Teitl
Term Framework for the Provision of Chemistry Synthesis and other Chemistry Services Outsourcing Framework
Cyfeirnod: UoD-LAB031-TC-2023
II.1.2) Prif god CPV
73110000
II.1.3) Y math o gontract
Gwasanaethau
II.1.4) Disgrifiad byr
Second-Generation Framework for the provision of Chemistry Synthesis and other Chemistry Services Outsourcing with initial term of two (2) years with the option to extend for up to 2 x 12 months, if required, at the sole discretion of the University and subject to ongoing satisfactory performance by the appointed Service Providers.
The Services will include:
1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important;
2.Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale;
3. Scale up of chemistry, up to 200g;
4.Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale.
5.Synthesis of intermediates at 5-100g;
For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%;
6. Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes.
II.1.5) Cyfanswm gwerth amcangyfrifedig
Gwerth heb gynnwys TAW: 4 000 000.00 GBP
II.1.6) Gwybodaeth am lotiau
Mae’r contract hwn wedi’i rannu’n lotiau:
Na
II.2) Disgrifiad
II.2.2) Cod(au) CPV ychwanegol
73110000
II.2.3) Man cyflawni
Cod NUTS:
UKM71
Prif safle neu fan cyflawni:
Biological Chemistry & Drug Discovery (BCDD), University of Dundee
II.2.4) Disgrifiad o’r caffaeliad
This Second-Generation Framework is required to provide a quick route to market for the provision of Chemistry Synthesis and other Chemistry Services. The initial contract term will be two (2) years, with the option to extend for 2 x 12 months, if required, at the sole discretion of BCDD and subject to ongoing satisfactory performance by the appointed Service Providers
The Chemistry Synthesis and Other Chemistry Services required will include:
1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important;
2. Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale;
-Scale up of chemistry, up to 200g;
-Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale.
-Synthesis of intermediates at 5-100g;
For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%;
-Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes.
The subsequent route to market will be via Mini Comp under the Framework.
II.2.5) Meini prawf dyfarnu
Maen prawf isod:
Maes prawf ansawdd: 1. Account /Project Management & Communication
/ Pwysoliad: 4
Maes prawf ansawdd: 2.Range of Chemistry Synthesis and other Chemistry Services available.
/ Pwysoliad: 10
Maes prawf ansawdd: 3. Service Levels
/ Pwysoliad: 10
Maes prawf ansawdd: 4. Audit Control & Record Keeping
/ Pwysoliad: 10
Maes prawf ansawdd: 5. Sample CVs
/ Pwysoliad: 2
Maes prawf ansawdd: 6. Added Value
/ Pwysoliad: 4
Price
/ Pwysoliad:
60
II.2.6) Gwerth amcangyfrifedig
Gwerth heb gynnwys TAW: 4 000 000.00 GBP
II.2.7) Hyd y contract, y cytundeb fframwaith neu’r system brynu ddynamig
Hyd mewn misoedd: 24
Gall y contract hwn gael ei adnewyddu: Ydy
Disgrifiad o’r adnewyddiadau:
Option to extend Framework for maximum 2 x further years, subject to ongoing need and satisfactory performance by the appointed service providers.
II.2.9) Gwybodaeth am y cyfyngiadau ar nifer yr ymgeiswyr a gaiff eu gwahodd
II.2.10) Gwybodaeth am amrywiadau
Derbynnir amrywiadau:
Na
II.2.11) Gwybodaeth am opsiynau
Opsiynau:
Na
II.2.13) Gwybodaeth am Gronfeydd yr Undeb Ewropeaidd
Mae'r broses gaffael yn gysylltiedig â phrosiect a/neu raglen a ariennir gan gronfeydd yr Undeb Ewropeaidd:
Na
Section III: Gwybodaeth gyfreithiol, economaidd, ariannol a thechnegol
III.1) Amodau ar gyfer cymryd rhan
III.1.1) Addasrwydd i ymgymryd â’r gweithgaredd proffesiynol, gan gynnwys gofynion mewn perthynas â chofrestru ar gofrestri proffesiynol neu gofrestri masnach
Rhestr a disgrifiad byr o’r amodau:
Please provide a minimum of 3 examples of similar projects/contracts previously undertaken in the last 3 years.
Please provide details of the technicians or technical bodies that you can call upon , particularly in respect of quality control of the Chemistry synthesis services to be provided:
Bidders are required to confirm that they and/or their proposed personnel have as a minimum the following relevant educational and professional qualifications:
Team Leaders with responsibility for the day-to-day management of UoD’s projects must be educated to PhD level or equivalent;
Chemists carrying out the project work require to be educated to BSC level or above;
III.1.2) Statws economaidd ac ariannol
Meini prawf dethol fel y’u nodir yn y dogfennau caffael
III.1.3) Gallu technegol a phroffesiynol
Meini prawf dethol fel y’u nodir yn y dogfennau caffael
III.2) Amodau sy’n gysylltiedig â’r contract
III.2.3) Gwybodaeth am y staff a fydd yn gyfrifol am gyflawni’r contract
Rhwymedigaeth i nodi enwau a chymwysterau proffesiynol y staff a glustnodwyd i gyflawni’r contract
Section IV: Gweithdrefn
IV.1) Disgrifiad
IV.1.1) Y math o weithdrefn
Gweithdrefn agored
IV.1.3) Gwybodaeth am gytundeb fframwaith neu system brynu ddynamig
The procurement involves the establishment of a framework agreement with several operators.
Uchafswm nifer y cyfranogwyr a ragwelir yn y cytundeb fframwaith: 6
IV.1.8) Gwybodaeth am Gytundeb Caffael y Llywodraeth (GPA)
The procurement is covered by the Government Procurement Agreement:
Ydy
IV.2) Gwybodaeth weinyddol
IV.2.2) Terfyn amser i dendrau neu geisiadau i gymryd rhan ddod i law
Dyddiad:
26/04/2024
Amser lleol: 17:00
IV.2.4) Ym mha iaith/ieithoedd y gellir cyflwyno tendrau neu geisiadau i gymryd rhan
EN
IV.2.6) Yr isafswm cyfnod gofynnol i’r sawl sy’n tendro gynnal y tendr
Rhaid i’r tendr fod yn ddilys tan:
31/05/2024
IV.2.7) Amodau ar gyfer agor tendrau
Dyddiad:
01/05/2024
Amser lleol: 12:00
Place:
Procurement, Level 3, Tower Building, University of Dundee, Nethergate, Dundee DD1 4HN
Gwybodaeth am bersonau awdurdodedig a'r weithdrefn agor:
Mary Kirkpatrick, Category Manager duly authorised.
Section VI: Gwybodaeth ategol
VI.1) Gwybodaeth am ailddigwydd
Caffaeliad cylchol yw hwn:
Na
VI.2) Gwybodaeth am lifau gwaith electronig
Defnyddir archebion electronig
Derbynnir anfonebau electronig
Defnyddir taliadau electronig
VI.3) Gwybodaeth ychwanegol
NOTE: To register your interest in this notice and obtain any additional information please visit the Public Contracts Scotland Web Site at https://www.publiccontractsscotland.gov.uk/Search/Search_Switch.aspx?ID=761553.
The buyer has indicated that it will accept electronic responses to this notice via the Postbox facility. A user guide is available at https://www.publiccontractsscotland.gov.uk/sitehelp/help_guides.aspx.
Suppliers are advised to allow adequate time for uploading documents and to dispatch the electronic response well in advance of the closing time to avoid any last minute problems.
(SC Ref:761553)
Download the ESPD document here: https://www.publiccontractsscotland.gov.uk/ESPD/ESPD_Download.aspx?id=761553
VI.4) Gweithdrefnau adolygu
VI.4.1) Corff adolygu
Dundee Sheriff Court
West Bell Street
Dundee
DD1 1HN
UK
VI.4.2) Corff sy’n gyfrifol am weithdrefnau cyfryngu
Dundee Sheriff Court
West Bell Street
Dundee
DD1 4HN
UK
VI.5) Dyddiad anfon yr hysbysiad hwn
22/03/2024